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Prisms in the leading edge of the occlusal enamel form an average angle of 648 with the ̄at occluding surface of the enamel, but in the trailing region the prism angle averages 918 (Figure 18. Acta Psychiatr Scand 1989;79:378385. New York, Oxford University Press, 1993. (1994). The narcotic analgesics derived from opium produce their effects by binding to special receptors for naturally occurring brain chemicals called endorphins.

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